RFLPs at the D21S19 locus of human chromosome 21
نویسندگان
چکیده
منابع مشابه
RFLPs at the D19S19 locus of human chromosome 19 linked to myotonic dystrophy (DM)
SOURCE/DESCRIPTION: Probe LDR152-a 1.68 Kb single copy Hind III fragment isolated from a chromosome 19 bivariate flow sorted enriched Charon 21A library and subcloned into SP64. CHROMOSOMAL LOCALISATION: 1 9cent-1 9q 1 • 3 by somatic cell hybrid and linkage data. POLYMORPHISMS: Recognises two, two allele polymorphisms when U3ed to probe human genomic DNA digested with P3t I and Msp I.
متن کاملTwo RFLPs at the TNP1 locus.
Source/Description: The Human Transition Protein 1 gene (TNP1) probe (1) used was a 700 bp genomic DNA sequence cloned into the Smal site of pUC8 and was supplied by W.Engel. Polymorphisms: TNP1 identifies a two allele polymorphism with TaqI: Al = 9.6 kb; A2 = 8.4 kb. Frequency: Analysis of 20 unrelated individuals yielded frequencies: Al = 0.23; A2 = 0.77. Rsal in a screen of 10-20 unrelated i...
متن کاملThe DNA sequence of human chromosome 21 The chromosome 21 mapping and sequencing consortium
The chromosome 21 mapping and sequencing consortium M. Hattori*, A. Fujiyama*, T. D. Taylor*, H. Watanabe*, T. Yada*, H.-S. Park*, A. Toyoda*, K. Ishii*, Y. Totoki*, D.-K. Choi*, E. Soeda2, M. Ohki3, T. Takagi§, Y. Sakaki*§; S. Taudienk, K. Blechschmidtk, A. Polleyk, U. Menzelk, J. Delabar¶, K. Kumpfk, R. Lehmannk, D. Patterson#, K. Reichwaldk, A. Rumpk, M. Schillhabelk, A. Schudyk, W. Zimmerma...
متن کاملA second locus for Aicardi-Goutieres syndrome at chromosome 13q14-21.
BACKGROUND Aicardi-Goutières syndrome (AGS) is an autosomal recessive, early onset encephalopathy characterised by calcification of the basal ganglia, chronic cerebrospinal fluid lymphocytosis, and negative serological investigations for common prenatal infections. AGS may result from a perturbation of interferon alpha metabolism. The disorder is genetically heterogeneous with approximately 50%...
متن کاملMolecular genetics of human chromosome 21.
Chromosome 21 is the smallest autosome, comprising only about 1.9% of human DNA, but represents one of the most intensively studied regions of the genome. Much of the interest in chromosome 21 can be attributed to its association with Down's syndrome, a genetic disorder that afflicts one in every 700 to 1000 newborns. Although only 17 genes have been assigned to chromosome 21, a very large numb...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1985
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/13.19.7168